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With the effects of global warming, some epidemic diseases via mosquito (e.g. mosquito-borne diseases) become more serious, such as dengue fever and zika virus. It is reported that the epidemic disease may cause many challenges to the hospital management due to the unexpected burst with uncertain reasons. Furthermore, the imperfect cares during the propagation of epidemic diseases, such as dengue...
AMP-activated protein kinase (AMPK) is a metabolite- sensed protein kinase in various eukaryotes. The activated AMPK regulates important proteins which cause diabetes, obesity, metabolic aberrant, and also breast cancer. In this study, the yeast AMPK structure was used as a template to model the human AMPK structure. By homology modeling, the reliable AMPK structure was built, and the active binding...
This study theoretically analyzes and numerically explores the relationship between the physiological data and three diabetic microvascular complications: diabetic retinopathy, diabetic nephropathy, and diabetic neuropathy (foot problem). Method: The analysis results of 8,736 diabetic patients in northern Taiwan by using two data mining models: C5.0 and neural network were presented and compared....
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