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Multiple Antibiotikaresistenz bei Gram‐negativen Bakterien ist häufig mit einer reduzierten Permeabilität der Außenmembran verbunden. Hier quantifizieren wir den Beitrag von Membrankanälen bei der Aufnahme von Antibiotika. Hierzu untersuchen wir zwei Membrankanäle von E. coli, OmpF und OmpC. Diese werden jeweils in E. coli überexprimiert, äußere Membranvesikel (OMV) gesammelt und mit planaren Lipiddoppelschichten...
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