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In order to improve property of bacterial nano-cellulose (BNC) to achieve the requirements of clinical application as small caliber vascular grafts, chitosan (CH) was deposited into the fibril network of the BNC tubes fabricated in unique Double-Silicone-Tube bioreactors. Heparin (Hep) was then chemically grafted into the BNC-based tubes using EDC/NHS crosslinking to improve performance of anticoagulation...
Aqueous mixture of NaOH/urea/thiourea at a 8/8/6.5 composition and pre-cooled at −10°C readily dissolved cellulose to produce stable solutions at relatively high concentrations. The exothermic dissolution process was favored at −2 to 0°C. Aqueous NaOH/urea/thiourea solution as non-derivatizing solvent broke the intra- and inter-molecular hydrogen bonding of cellulose and prevented the approach toward...
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