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The skip metastasis (SM) of axillary lymph nodes (ALN) in breast cancer is an important phenomenon which is crucial to determine the correct choice of surgical resection. The mechanism of SM of ALN is unclear. Gli1 protein is a core epithelial-to-mesenchymal transition (EMT) regulatory factor that plays essential roles in both development and disease processes and has been associated with metastasis...
Fascin, an actin‐cross‐linking protein, is up‐regulated in breast cancer and correlates with a more aggressive disease. This study was conducted to elucidate the effects of manipulating fascin in breast cancer cells on the metastasis‐associated events, including proliferation, adhesion, invasion, epithelial–mesenchymal transition (EMT) and enrichment of a CD44+/CD24− subpopulation that show some stem/progenitor...
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