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The study evaluates the role of human skull composition and brain anisotropy in the context of transcranial direct current stimulation (tDCS) based predictive modeling. Four head models were developed and each proposed attribute (cancellous bone and brain anisotropy) was compared with the isotropic model. By employing a single high-definition montage, the efficacy of each attribute in shaping induced...
Biological tissues are multi-compartmental inhomogeneous media composed of different cellular and subcellular domains. Human head, a multi-compartmental inhomogeneous medium, is composed of scalp, skull, cerebrospinal fluid (CSF), gray matter (GM), white matter (WM), and other subcellular domains. Among these domains, skull and WM show the complicated anisotropy tissue property because of their physiological...
The aim of this study is to investigate the effects of white matter (WM) and skull inhomogeneous anisotropic tissue conductivities on human head modeling. The inhomogeneity of WM and skull is included using fractional anisotropy (FA) method and the anisotropy is included according to volume constraint in the head model construction. A five-layered spherical head model implemented using finite element...
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