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Background
Studies suggesting a protective effect of estrogen in neurodegenerative diseases prompted us to investigate this relationship in progressive supranuclear palsy (PSP).
Methods
This case‐control study evaluated the self‐reported reproductive characteristics and estrogen of 150 women with PSP and 150 age‐matched female controls who participated in the Environmental Genetic‐PSP study. Conditional...
J. Neurochem. (2010) 113, 674–682.
AbstractParkinson’s disease (PD) is associated with perturbed mitochondrial function. Studies of cytoplasmic hybrid (cybrid) cell lines containing mitochondria from PD subjects suggest complex I dysfunction in particular is a relatively upstream biochemical defect. To evaluate potential downstream consequences of PD mitochondrial dysfunction, we used a cybrid approach...
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