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BackgroundB lymphocytes are an important cell population of the immune regulation; their role in the regulation of food allergy has not been fully understood yet.
ObjectiveThis study aims to investigate the role of a subpopulation of tolerogenic B cells (TolBC) in the generation of regulatory T cells (Treg) and in the suppression of food allergy‐induced intestinal inflammation in mice.
MethodsThe...
To cite this article: Chen X, Song C‐H, Liu Z‐Q, Feng B‐S, Zheng P‐Y, Li P, In SH, Tang S‐G, Yang P‐C. Intestinal epithelial cells express galectin‐9 in patients with food allergy that plays a critical role in sustaining allergic status in mouse intestine. Allergy 2011; 66: 1038–1046.
AbstractBackground and aims: Mechanisms in sustaining the allergic hypersensitivity status in the body are unclear...
The mechanism underlying late‐phase allergic reactions (LPR) remains incompletely understood. This study aimed to investigate the role of a newly described subset of T cells, interleukin (IL)‐9+ IL‐10+ T cells, in the pathogenesis of LPR. Using a T helper type 2 (Th2) inflammatory mouse model, we examined the frequency of IL‐9+ IL‐10+ T cells in the jejunum by immunohistochemistry. The LPR in the...
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