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BackgroundIn most patients pseudoxanthoma elasticum (PXE) manifests with yellowish cutaneous papules and dermal elastorrhexis on skin biopsy. In a small number of cases there are no skin manifestations on clinical examination, and establishing a diagnosis of PXE in such patients is challenging. High‐frequency ultrasonography (HFUS) may be of use in predicting skin areas that would yield a biopsy specimen...
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