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The aim of this study was to determine the effects of sub-chronic aluminum chloride (AlCl 3 ) on spermatogenesis and testicular enzymatic activity in male rats.Forty Wistar male rats were randomly divided into four groups: control group (CG, 0), low-dose group (LG, 64.18mg/kg BW AlCl 3 ), mid-dose group (MG, 128.36mg/kg BW AlCl 3 ) and high-dose group (HG, 256.72mg/kg BW AlCl...
Status epilepticus (SE) is a grave condition in which the brain undergoes lasting seizures which can lead to neuronal loss. Our previous study suggested that preconditioning with erythropoietin (Epo) suppressed neuronal apoptosis in hippocampus of rats following SE in vivo by inhibiting caspase-3. In this study, we investigated the mechanisms by which Epo preconditioning may exert its anti-apoptotic...
Complete or partial spinal section at T 8 has been shown to block tactile allodynia but not thermal hyperalgesia following L 5 /L 6 spinal nerve ligation (SNL), suggesting the supraspinal integration of allodynia in neuropathic pain. In the present study, the possibility of mediation of nerve injury-associated pain through tonic activity of descending nociceptive facilitation...
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