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Alzheimer's disease (AD) is the most common neurodegenerative disorder among older people. However, no cure or disease-modifying treatments are currently available, and the molecular and cellular mechanisms responsible for the etiology of AD remain under debate. Recent studies suggest that the immune system has a crucial role in AD pathogenesis and, thus, immunotherapy might be a promising new treatment...
Alzheimer's disease (AD) is the most common form of senile dementia and the fourth highest cause of disability and death in the elderly. Amyloid-β (Aβ) has been widely implicated in the etiology of AD. Several mechanisms have been proposed for Aβ clearance, including receptor-mediated Aβ transport across the blood–brain barrier and enzyme-mediated Aβ degradation. Moreover, pre-existing immune responses...
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