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We investigated the association between IL-1, IL-1ra, and TNF- gene polymorphisms and childhood nephrotic syndrome (NS). We analyzed the genetic polymorphism of IL-1, IL-1ra, and TNF- genes in 152 patients with childhood NS and 292 healthy adult controls. The C to T exchange at position 511 of IL-1 and the G to A at 308 of the TNF- gene were genotyped. Five alleles of the IL-1ra gene were identified...
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