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In article number 1805552, Hua Zuo, Chengde Mao, and co‐workers describe an elegant method to assemble DNA microparticles (DNAµPs), relying on self‐assembly of multiple copies of the same, short, component DNA strand. The resulting DNAµPs can present single stranded DNA tails on their surfaces to stimulate innate immune responses and capture other single‐stranded nucleic acids.
DNA is a superb molecule for self‐assembly of nanostructures. Often many DNA strands are required for the assembly of one DNA nanostructure. For lowering the cost of synthesizing DNA strands and facilitating the assembly process, it is highly desirable to use a minimal number of unique strands for potential technological applications. Herein, a strategy is reported to assemble a series of DNA microparticles...
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