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Optical molecular imaging can characterize and monitor multi molecular events in vivo, which providing a practical tool for early tumor diagnosis and drug development. To establish a research platform for optical molecular imaging, we develop the fluorescent protein-based genetically encoded optical probes, lipoprotein-based multi-functional nanocarrier, and optical molecular imaging systems.
It has been identified that insulin was present in the central nervous system (CNS) with some types of action there, and it exerted important actions within the brain and functions as neuropeptide. Insulin should bind with insulin receptors (IR) to perform its functions, so it is important to study the binding of insulin with IR in neurons. A direct imaging method was developed by fluorescence microscopy...
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