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BACKGROUND:A study was conducted to determine the 5‐year recurrence‐free survival in patients with high‐risk prostate cancer after neoadjuvant combination chemotherapy followed by surgery. Secondary endpoints included safety, pathologic effects of chemotherapy, and predictors of disease recurrence.
METHODS:Fifty‐seven patients were enrolled in a phase 1/2 study of weekly docetaxel 35 mg/m2 and escalating...
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