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Purpose
To propose and assess an improved method for calculating the equilibrium magnetization of arterial blood (
), used for calibration of perfusion estimates in arterial spin labeling.
Methods
Whereas standard
calculation is based on dividing a proton density–weighted image by an average brain–blood partition coefficient, the proposed method exploits partial‐volume data to adjust this...
Quantitative perfusion MRI based on arterial spin labeling (ASL) is hampered by partial volume effects (PVEs), arising due to voxel signal cross‐contamination between different compartments. To address this issue, several partial volume correction (PVC) methods have been presented. Most previous methods rely on segmentation of a high‐resolution T1‐weighted morphological image volume that is coregistered...
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