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Core-shell structured PEO/HA nanofibers could be produced from electric field inducing phase separation during the electrospinning progress. Hyaluronic acid (HA) molecules could move along the opposite direction of the electric field under the electrostatic force, which induced phase separation from PEO to form the core layer of nanofibers. The morphology of core–shell nanofibers was supported using...
The hyaluronic acid (HA) fibers scaffold with an extracellular matrix mimic structure has been prepared via lyophilization. The morphology of the HA fibers varying the concentration from 0.05wt% to 0.15wt% was characterized by scanning electron microscope (SEM). The diameter of HA fibers increased and the morphology changed from fiber to sheet-like structure as the concentration of HA solution increased...
A highly porous chitosan nanofibers were obtained by electrospinning chitosan/polyethylene oxide (PEO) blend solutions and then removing PEO with water. The porous morphology of the nanofibers was observed by scanning electron microscopy. The porous nanofibers were soaked in 0.1wt% paclitaxel solution to load the cancer drug. Then a polyanion nature macromolecular hyaluronic acid (HA) was encapsulated...
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