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Résumé Pendant plus de 30 ans, la prise en charge thérapeutique du carcinome hépatocellulaire (CHC) aux stades avancés a été limitée par les résultats médiocres des molécules cytotoxiques conventionnelles dont les bénéfices sont restreints à une faible proportion de patients. Le développement ultérieur des thérapies moléculaires ciblées dans le CHC répondait à un fort rationnel. En effet, le CHC est...
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