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Background and Purpose
Tooth eruption is a complicated process regulated by the dental follicles (DF). Our recent study discovered that tooth eruption was inhibited upon injection of bleomycin into DF. However, the mechanisms were unknown.
Experimental Approach
Human dental follicle cells (hDFCs) were treated by bleomycin or exogenous TGF‐β1 or transfected by plasmids loading SMAD7 or shRNA targeting...
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