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Patients with recurrent cancer of the head and neck involving the base of the skull have limited treatment options. Stereotactic radiosurgery is currently being investigated as a viable modality of treatment for these patients. This paper reviews the basic principles and treatment procedures involved in stereotactic radiosurgery, as well as published reports on its use with these patients. Finally,...
The rationale and current supporting evidence for a complementary, multi-agent, low-toxicity, chronic, cytostatic therapeutic approach to treating patients with gliomas is presented in detail. This strategy would involve the simultaneous treatment of patients with DNA/chromosomal stabilizing agent(s), anti-angiogenesis agent(s), and antiinvasion agent(s), with or without the addition of a lowtoxicity...
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