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Sialyltransferases have received much attention recently as they are frequently up-regulated in cancer cells. However, the role played by each sialyltransferase in tumour progression is still unknown. α2,3-Sialyltransferases ST3Gal III and ST3Gal IV are involved in sialyl-Lewis x (SLe x ) synthesis. Given that the role of ST3Gal III in pancreatic adenocarcinoma cells has been previously...
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