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Mesenchymal chondrosarcoma is a rare but deadly form of chondrosarcoma that typically affects adolescents and young adults. While curative intent is possible for patients with localized disease, few options exist for patients in the unresectable/metastatic setting. Thus, it is imperative to understand the fusion-driven biology of this rare malignant neoplasm so as to lead to the future development...
Melanoma can rarely show malignant chondro‐osseous differentiation and can cause diagnostic confusion. We report 3 cases of primary melanoma with extensive bone and cartilage matrix. The first case arose in the nasal mucosa of a 72‐year‐old woman, the second case in the left index finger of a 26‐year‐old woman and the third case in the left cheek of a 68‐year‐old woman. In tumors where osseous and...
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