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Background To determine reference intervals for serum levels of human epididymis protein 4 (HE4) in Chinese women. Methods In this multicenter (n = 9) study, 618 healthy women, 767 patients with non-malignant diseases, and 951 patients with malignant tumors were enrolled. Serum levels of HE4 were measured in all patients using electrochemiluminescence immunoassays. The influence of age, menopause,...
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