Search results for: Chang Liu

Items from 1 to 20 out of 2,388 results

article

Abnormal resting-state cerebral-limbic functional connectivity in bipolar depression and unipolar depression

Chang Liu, Weidan Pu, Guowei Wu, Jie Zhao, more

BMC Neuroscience > 2019 > 20 > 1 > 1-8

Background Distinctive patterns of functional connectivity (FC) abnormalities in neural circuitry has been reported in patients with bipolar depression (BD) and unipolar depression (UD). However, it is unclear that whether this distinct functional connectivity patterns are diagnosis specific between BD and UD. This study aimed to compare patterns of functional connectivity among BD, UD and healthy...

article

Overexpression miR‐24‐3p repressed Bim expression to confer tamoxifen resistance in breast cancer

Xu Han, Qiaobei Li, Chang Liu, Chunyan Wang, more

Journal of Cellular Biochemistry > 120 > 8 > 12966 - 12976

Endocrine therapy resistance represents a major challenge to the successful treatment of patients with breast cancer. The development of tamoxifen resistance commonly occurrs during the treatment of patients with breast cancer whereas its underlying mechanisms remain elusive. Here, we found that miR‐24‐3p regulated tamoxifen sensitivity in breast cancer cells. Forced overexpression of miR‐24‐3p augmented...

article

Inhibition of miR-19a protects neurons against ischemic stroke through modulating glucose metabolism and neuronal apoptosis

Xiao-Li Ge, Jin-Li Wang, Xin Liu, Jia Zhang, more

Cellular & Molecular Biology Letters > 2019 > 24 > 1 > 1-11

Background Accumulating evidence has shown that altered microRNA (miR) modulation is implicated in the pathologies of ischemic stroke. However, it is unclear whether and how hsa-miR-19a-3p mediates cerebral ischemic injury. Herein, we investigated the functional role of miR-19a-3p in cerebral ischemic injury and explored its underlying regulatory mechanism. Methods In vivo ischemic/reperfusion (I/R)...

article

Restraint use and injury in forward and rear-facing infants and toddlers involved in a fatal motor vehicle crash on a U. S. Roadway

Yu-Yun Huang, Chang Liu, Joyce C. Pressley

Injury Epidemiology > 2019 > 6 > 1 > 1-11

Background Use of appropriate child passenger safety restraints reduces injury in infants, with rear facing restraints favored over forward facing. In 2011, the American Academy of Pediatrics (AAP) began recommending that infants and children under the age of 2 years be restrained in a rear-facing seat installed in the vehicle’s rear seat. This study examines the practice of rear-facing restraints...

article

Tuning Electronic Properties of Blue Phosphorene/Graphene-Like GaN van der Waals Heterostructures by Vertical External Electric Field

Jingjing Guo, Zhongpo Zhou, Hengheng Li, Haiying Wang, more

Nanoscale Research Letters > 2019 > 14 > 1 > 1-7

The structural and electronic properties of a monolayer and bilayer blue phosphorene/graphene-like GaN van der Waals heterostructures are studied using first-principle calculations. The results show that the monolayer-blue phosphorene/graphene-like GaN heterostructure is an indirect bandgap semiconductor with intrinsic type II band alignment. More importantly, the external electric field tunes the...

article

Precipitation Behavior of Spherical γ′ Phase in Eutectic Area of Ni₃Al‐Based Alloy

Xing Chuan Xia, Yuan Yi Peng, Xin He, Chong Li, more

Advanced Engineering Materials > 21 > 5 > n/a - n/a

Understanding and mastering initial status in eutectic area (γ′–γ) of Ni₃Al‐based alloy under solution treatment conditions are beneficial to its aging treatment and applications. In this work, optimal solution treatment process parameters of JG4246A Ni₃Al‐based alloy are investigated based on microstructure observation, chemical composition analysis, and micro‐hardness test. Results show that the...

article

Cell‐specific elevation of Runx2 promotes hepatic infiltration of macrophages by upregulating MCP‐1 in high‐fat diet‐induced mice NAFLD

Li Zhong, Lu Huang, Qian Xue, Chang Liu, more

Journal of Cellular Biochemistry > 120 > 7 > 11761 - 11774

Objective We have demonstrated runt‐related transcription factor 2 (Runx2) plays important role in atherosclerosis. It has been indicated that atherosclerosis shares the similar histopathology with nonalcoholic steatohepatitis (NASH), a progressive stage of nonalcoholic fatty liver disease (NAFLD), on macrophages infiltration. However, the function of Runx2 in NAFLD is completely unknown. Here, we...

article

Visible to Near‐Infrared Photodetection Based on Ternary Organic Heterojunctions

Wei Li, Yalun Xu, Xianyi Meng, Zuo Xiao, more

Advanced Functional Materials > 29 > 20 > n/a - n/a

Organic semiconductors have attracted tremendous attention in the past few years, thanks to their excellent flexibility, solution‐processability, low‐cost, chemical versatility, etc. Particularly, organic solar cells based on ternary heterojunctions have shown remarkable device performance, with the recent development of nonfullerene acceptor materials. These novel materials are also promising for...

article

The polarization characteristics of lithium-ion batteries under cyclic charge and discharge

Changsheng Qiu, Gang He, Wankai Shi, Mengjie Zou, more

Journal of Solid State Electrochemistry > 2019 > 23 > 6 > 1887-1902

A high-fidelity electrochemical-thermal coupling was established to study the polarization characteristics of power lithium-ion battery under cycle charge and discharge. The lithium manganese oxide lithium-ion battery was selected to study under cyclic conditions including polarization voltage characteristics, and the polarization internal resistance characteristics of the power lithium-ion battery...

article

A Sensitive Aptasensor Based on a Hemin/G‐Quadruplex‐Assisted Signal Amplification Strategy for Electrochemical Detection of Gastric Cancer Exosomes

Rongrong Huang, Lei He, Yanyan Xia, Hongpan Xu, more

Small > 15 > 19 > n/a - n/a

Emerging evidence indicates that exosomes derived from gastric cancer cells enhance tumor migration and invasion through the modulation of the tumor microenvironment. However, it remains a major problem to detect cancer‐specific exosomes due to technical and biological challenges. Most of the methods reported could not achieve efficient detection of tumor‐derived exosomes in the background of normal...

article

Anesthetic management of gigantic pheochromocytoma resection with inferior vena cava and right atrium tumor thrombosis: a case report

Jingli Chen, Caihua Liu, Chang Liu, Quanyuan Fu, more

BMC Anesthesiology > 2019 > 19 > 1 > 1-6

Background This report describes one case of anesthetic management about surgical resection of a malignant phaeochromocytoma with tumor extension into vena cava and right atrium in a patient. Report for anesthetic management is limited in these patients under surgical resection until now. Case presentation In September 2015, a 24-year-old male presented to the department of cardiology with right...

article

Prinzipien und Grundlagen der Wahrnehmungsauffassung bei Husserl

Chang Liu

Husserl Studies > 2019 > 35 > 2 > 149-176

“Apprehension” (Auffassung) is a key term in Husserl’s phenomenology of perceptual consciousness. However, its modes of operation have not yet been closely analyzed. Apprehension has its own principles and foundations. According to Husserl, the principles of apprehension are 1) contiguity, 2) equality and 3) similarity, and each of them expresses a specific kind of qualitative connection between the...

article

LncRNA SNHG1 contributes to sorafenib resistance by activating the Akt pathway and is positively regulated by miR-21 in hepatocellular carcinoma cells

Weidong Li, Xuesong Dong, Changjun He, Gang Tan, more

Journal of Experimental & Clinical Cancer Research > 2019 > 38 > 1 > 1-13

Background Acquired resistance to sorafenib greatly limits its therapeutic efficiency in the treatment of hepatocellular carcinoma (HCC). Increasing evidence indicates that long noncoding RNAs (lncRNAs) play important roles in the resistance to anti-cancer drugs. The present study aims to explore the involvement of lncRNA SNHG1 (small nucleolar RNA host gene 1) in sorafenib resistance and how SNHG1...

article

Hot deformation behaviors of a 9Cr oxide dispersion-strengthened steel and its microstructure characterization

Yu Shao, Li-ming Yu, Yong-chang Liu, Zong-qing Ma, more

International Journal of Minerals, Metallurgy, and Materials > 2019 > 26 > 5 > 597-610

The hot deformation behaviors of a 9Cr oxide dispersion-strengthened (9Cr-ODS) steel fabricated by mechanical alloying and hot isostatic pressing (HIP) were investigated. Hot compression deformation experiments were conducted on a Gleeble 3500 simulator in a temperature range of 950–1100°C and strain rate range of 0.001–1 s⁻¹. The constitutive equation that can accurately describe the relationship...

article

Plant lamin-like proteins mediate chromatin tethering at the nuclear periphery

Bo Hu, Nan Wang, Xiuli Bi, Ezgi Süheyla Karaaslan, more

Genome Biology > 2019 > 20 > 1 > 1-18

Background The nuclear envelope not only serves as a physical barrier separating nuclear content from the cytoplasm but also plays critical roles in modulating the three-dimensional organization of genomic DNA. For both plants and animals, the nuclear periphery is a functional compartment enriched with heterochromatin. To date, how plants manage to selectively tether chromatin at the nuclear periphery...

article

All-trans-retinoic acid (ATRA) plus oxaliplatin plus 5-fluorouracil/leucovorin (FOLFOX) versus FOLFOX alone as palliative chemotherapy in patients with advanced hepatocellular carcinoma and extrahepatic metastasis: study protocol for a randomized controlled trial

Jie Shi, Juxian Sun, Chang Liu, Zongtao Chai, more

Trials > 2019 > 20 > 1 > 1-9

Background Among patients with hepatocellular carcinoma (HCC), 85% of patients have an advanced disease stage at diagnosis and curative therapies cannot be performed. Prognosis has been quite poor as until recently there was no proven effective chemotherapy. Our group found that all-trans-retinoic acid (ATRA) could improve the efficacy of platinum in HCC in vivo and in vitro, thus we wish to validate...

article

TPP1 OB-fold domain protein suppresses cell proliferation and induces cell apoptosis by inhibiting telomerase recruitment to telomeres in human lung cancer cells

Jinfang Zhu, Weiran Liu, Chen Chen, Hua Zhang, more

Journal of Cancer Research and Clinical Oncology > 2019 > 145 > 6 > 1509-1519

Purpose Maintaining telomeres by recruiting telomerase-to-chromosome ends is essential for cancer cell survival. Inhibiting telomerase recruitment to telomeres represents a novel strategy for telomere-based lung cancer therapy. However, approaches for interrupting telomerase recruitment for cancer therapy still need to be explored. Methods The telomere-binding protein TPP1 is responsible for recruiting...

article

Correlation of exfoliation performance with interlayer cations of montmorillonite in the preparation of two‐dimensional nanosheets

Haoyu Bai, Yunliang Zhao, Xian Zhang, Wei Wang, more

Journal of the American Ceramic Society > 102 > 7 > 3908 - 3922

Montmorillonite (MMT) can be exfoliated into nanosheets used in a wide range of applications as two‐dimensional (2D) material. The exfoliated MMT nanosheets with high diameter–thickness ratio appear to show superior properties in preparation of nanocomposites and other functional materials. In this work, the correlation of exfoliation performance with interlayer cations of MMT in the preparation of...

article

Polarization‐Sensitive Ultraviolet Photodetection of Anisotropic 2D GeS₂

Yusi Yang, Shun‐Chang Liu, Xia Wang, Zongbao Li, more

Advanced Functional Materials > 29 > 16 > n/a - n/a

Polarization‐sensitive photodetection in the UV region is highly indispensable in many military and civilian applications. UV‐polarized photodetection usually relies on the use of wide bandgap semiconductors with 1D nanostructures requiring complicated nanofabrication processes. Although the emerging anisotropic 2D semiconductors shed light on the detection of polarization with a simple device architecture,...

article

Autophagy mediates serum starvation-induced quiescence in nucleus pulposus stem cells by the regulation of P27

Bin Li, Chao Sun, Jing Sun, Ming-hui Yang, more

Stem Cell Research & Therapy > 2019 > 10 > 1 > 1-12

Background Adult stem cells exist in a quiescent state (G0) within the in vivo niche; the loss of quiescence often leads to a decrease in the number and function of adult stem cells, impairing tissue regeneration and repair. Endogenous repair by nucleus pulposus-derived stem cells has recently shown promising regenerative potential for the treatment of intervertebral disc degeneration (IDD). However,...

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INFONA - science communication portal

Search results for: Chang Liu

Abnormal resting-state cerebral-limbic functional connectivity in bipolar depression and unipolar depression

Overexpression miR‐24‐3p repressed Bim expression to confer tamoxifen resistance in breast cancer

Inhibition of miR-19a protects neurons against ischemic stroke through modulating glucose metabolism and neuronal apoptosis

Restraint use and injury in forward and rear-facing infants and toddlers involved in a fatal motor vehicle crash on a U. S. Roadway

Tuning Electronic Properties of Blue Phosphorene/Graphene-Like GaN van der Waals Heterostructures by Vertical External Electric Field

Precipitation Behavior of Spherical γ′ Phase in Eutectic Area of Ni₃Al‐Based Alloy

Cell‐specific elevation of Runx2 promotes hepatic infiltration of macrophages by upregulating MCP‐1 in high‐fat diet‐induced mice NAFLD

Visible to Near‐Infrared Photodetection Based on Ternary Organic Heterojunctions

The polarization characteristics of lithium-ion batteries under cyclic charge and discharge

A Sensitive Aptasensor Based on a Hemin/G‐Quadruplex‐Assisted Signal Amplification Strategy for Electrochemical Detection of Gastric Cancer Exosomes

Anesthetic management of gigantic pheochromocytoma resection with inferior vena cava and right atrium tumor thrombosis: a case report

Prinzipien und Grundlagen der Wahrnehmungsauffassung bei Husserl

LncRNA SNHG1 contributes to sorafenib resistance by activating the Akt pathway and is positively regulated by miR-21 in hepatocellular carcinoma cells

Hot deformation behaviors of a 9Cr oxide dispersion-strengthened steel and its microstructure characterization

Plant lamin-like proteins mediate chromatin tethering at the nuclear periphery

All-trans-retinoic acid (ATRA) plus oxaliplatin plus 5-fluorouracil/leucovorin (FOLFOX) versus FOLFOX alone as palliative chemotherapy in patients with advanced hepatocellular carcinoma and extrahepatic metastasis: study protocol for a randomized controlled trial

TPP1 OB-fold domain protein suppresses cell proliferation and induces cell apoptosis by inhibiting telomerase recruitment to telomeres in human lung cancer cells

Correlation of exfoliation performance with interlayer cations of montmorillonite in the preparation of two‐dimensional nanosheets

Polarization‐Sensitive Ultraviolet Photodetection of Anisotropic 2D GeS₂

Autophagy mediates serum starvation-induced quiescence in nucleus pulposus stem cells by the regulation of P27

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