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Background Based on the known inflammatory role of interleukins (IL), we evaluated IL-1β and IL-6 expressions and their association with the severity of traumatic brain injury (TBI; Glasgow Coma Scale [GCS]) and the outcome (Glasgow Outcome Score [GOS]) recorded in a paediatric population. Design The design was a perspective observational clinical study carried out in the paediatric intensive care...
Objectives. We evaluated the neurotrophic factors [nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), glia-derived neurotrophic factor (GDNF)] expression and their association with the severity and outcome of children with traumatic brain injury. Design. Prospective observational clinical study. Setting. Pediatric intensive care unit. Patients. Fourteen children with severe head...
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