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Regenerating articular cartilage is a challenge for orthopedic surgery. Advanced therapeutical medicinal products (ATMP, including gene therapy, cell therapy, tissue engineering products) are offering promising solutions to structurally and functionally replace missing or degenerated musculoskeletal tissues. The paper reviews current cell based clinical available procedures as well as potential cell...
Challenging the centuries, old statement cartilage do not regenerate, several, reports are describing, the presence of, condroprogenitor populations within ostheoarthritic cartilage., Osteophytes are non-osteoplastic protrusions, which, are formed gradually into an OA joint, into certain predictable, anatomical locations., Known to be related to evolution and progress of the disease, osteophytes formation...
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