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Injectable Hydrogels
In article number 2206554, Lin Yu and co‐workers develop an injectable and thermosensitive hydrogel with inherent long‐acting NO‐releasing capacity. The hydrogel system loaded with β‐lapachone and CuCys nanoparticles can synchronously boost intracellular reactive oxygen species and reactive nitrogen species levels, thereby synergistically enhancing the anti‐tumor efficacy. This...
Reactive nitrogen species (RNS) generated via the reaction of nitric oxide (NO) with reactive oxygen species (ROS) are more lethal than ROS, and thus RNS‐mediated therapy has great potential in cancer treatment, yet it is still largely unexploited. Herein, a novel, injectable and NO‐releasing hydrogel (NO‐Gel) composed of α‐(nitrate ester) acetic acid‐modified amphiphilic copolymers is developed....
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