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This study purposes to assess the cytotoxicity of 1‐dodecyl‐3‐methylimidazolium chloride ([C12min]Cl) in human hepatocellular carcinoma (HepG2) cells. To this end, HepG2 cells were exposed to a range concentration of [C12min]Cl and evaluated cell viability, genotoxicity, oxidative stress, apoptosis, cell cycle, and apoptosis‐related gene expression to determine cytotoxicity. The outcomes showed that...
Polychlorinated biphenyl (PCB) quinones are known to cause toxic effects, but their mechanisms are quite unclear. In this study, we examined whether 2,3,5‐trichloro‐6‐phenyl‐[1,4]benzoquinone, PCB29‐pQ, induces cell death via apoptosis pathway. Our result showed PCB29‐pQ exposure decreased HepG2 cell viability in a time‐dependent manner. Lactate dehydrogenase leakage assay also implied the cytotoxicity...
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