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To evaluate the potential of anthocyanin as a supplement for the treatment of Peyronie disease (PD) by examining the anti-inflammatory and antifibrosis activities of anthocyanin in a PD animal model.We performed the preliminary experiment to confirm the plaque formation of tunica albuginea (TA). Six animals received fibrin (TISSEEL VH Sealer; Baxter, Glendale, CA; 30 μL each of human fibrin and thrombin...
To explore the therapeutic potential of PnTx2-6 injected 3 times a week for 4 weeks into the intracavernosal tissue in a rat model of bilateral cavernous nerve crush injury (BCNI).Eight-week-old male Sprague-Dawley rats were randomly divided into the following 6 groups (n = 5 per group): age-matched control (normal group), BCNI (injury group), post-BCNI phosphate-buffered saline injection (PBS group),...
To show the noninferiority of silodosin 8-mg once-daily (QD) to 4-mg twice-daily (BID) in efficacy and safety in patients with lower urinary tract symptoms or benign prostatic hyperplasia in the Korean population.A prospective, multicenter, double-blind, randomized, comparative study was conducted. A total of 532 male patients aged ≥50 years with lower urinary tract symptoms or benign prostatic hyperplasia...
To prevent cavernous nerve injury and corpus cavernosum apoptosis-induced erectile dysfunction (ED) after prostatectomy surgery, we investigated whether oral administration of udenafil combination with covering adipose-derived stem cells (ADSCs) and brain-derived neurotrophic factor (BDNF) immobilized poly-lactic-co-glycolic (PLGA) membrane on the injured cavernous nerve could further improve erectile...
To investigate the differences in the histopathologic and functional characteristics of 3 rat models of stress urinary incontinence.A total of 24 female, 10-week-old, Sprague-Dawley rats were randomly divided into 4 groups: normal, electrocauterization, pudendal denervation, and vaginal distension. At 2 weeks after surgery, the leak point pressure was measured to detect urinary leakage. Urethral tissue...
To present our experience of 2-port laparoscopic donor nephrectomy (TPLDN) and to introduce a simple retraction suture technique.From October 2010 to November 2010, 10 consecutive, left TPLDNs were performed. The SILS Port was inserted through the umbilicus and was used for 5-mm laparoscope and laparoscopic instruments. A 12-mm trocar, for another working channel, was inserted along the midclavicular...
To investigate the effect of human muscle–derived stem cells (hMDSCs) on ameliorating impaired detrusor contractility in a cryoinjured bladder murine model. The hMDSCs were isolated and cultured by modified preplate technique, and only CD34-positive hMDSCs were extracted by Mini-MACS kits. Isolated hMDSCs were prelabeled with PKH26 and injected into the cryoinjured bladder to observe the pattern...
To survey cases of benign prostatic hyperplasia (BPH) among patients visiting urologists with lower urinary tract symptoms (LUTS) at general hospitals in Korea and to investigate treatment outcomes in current clinical practice. This was a multicenter, prospective study conducted in 18 urology centers in Korea. The symptoms of BPH were observed via the International Prostate Symptoms Score (IPSS),...
An extremely rare case of ureteral entrapment caused by traumatic lumbar spine injury with a duplication anomaly is presented. The patient was successfully managed in a minimally invasive fashion with laparoscopic excision and ureteroureterostomy.
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