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We macroscopically classified 25 gastric and 23 colorectal advanced cancers into contracted and uncontracted types, and found immunohistochemically that integrin subunit α3 was more frequently expressed in the extracellular matrix (ECM) in the former than in the latter (75%:9 vs. 38%: 5 in gastric and 86%:6 vs. 25%:4 in colorectal cancers, respectively). Integrin subunit α3 was also expressed...
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