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Objective
To evaluate whether chromosomal microarray (CMA) should be offered to fetuses with ultrasonographic soft markers (USMs) in the second trimester.
Methods
A prospective cohort study and meta‐analysis were conducted. In the prospective cohort study, 564 fetuses with USMs were enrolled. In the meta‐analysis, eligible articles describing copy number variations in fetuses with USMs were included...
Objective
To evaluate the usefulness and incremental diagnostic yield of chromosomal microarray analysis (CMA) compared with standard karyotyping in fetuses with congenital anomalies of the kidney and urinary tract (CAKUT).
Methods
A prospective cohort study and systematic review of the literature were conducted. In the prospective cohort study, 123 fetuses with CAKUT, as detected by prenatal ultrasound...
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