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Antiangiogenesis is a promising approach to cancer therapy but is limited by the lack of tumor‐homing capability of the current antiangiogenic agents. Angiogenin, a protein overexpressed and secreted by tumors to trigger angiogenesis for their growth, has never been explored as an antiangiogenic target in cancer therapy. Here it is shown that filamentous fd phage, as a biomolecular biocompatible nanofiber,...
Nontoxic phage virus nanofibers are genetically engineered by Mingying Yang, Chuanbin Mao, and co‐workers in article number 2001260 to first home to tumors through the blood circulation and then capture proteins that can promote blood vessel formation in the tumors. The phages are thus able to suppress tumor growth due to the inhibition of the tumor angiogenesis.
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