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Chronic antibody‐mediated rejection of kidney transplantation is a major cause of late‐stage graft loss. Donor‐specific antibodies are the main cause of antibody‐mediated rejection; in particular, de novo donor‐specific antibodies are a risk factor for chronic active antibody‐mediated rejection. The level of de novo donor‐specific antibodies tends to increase with time throughout long‐term graft survival...
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