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To elucidate whether nitric oxide excreted from irradiated cells affects cellular radiosensitivity, we examined (a) the accumulation of inducible nitric oxide synthase, p53 and Hsp70, (b) the concentration of nitrite in the medium of cells after irradiation with X-rays, and (c) cellular radiosensitivity using two human glioblastoma cell lines, A-172, having the wild type p53 gene, and transfectant...
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