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Objective
To determine changes in glucose metabolism and the enzymes involved in the hippocampus ictally and postictally in the acute mouse flurothyl seizure model.
Methods
[U‐13C]‐Glucose was injected (i.p.) prior to, or following a 5 min flurothyl‐induced seizure. Fifteen minutes later, mice were killed and the total metabolite levels and % 13C enrichment were analyzed in the hippocampal formation...
Benzo[α]pyrene (BaP) elicited a dose-response induction of hepatic CYP1A1 gene expression in killifish characterized by increased CYP1A1 mRNA levels, ethoxyresorufin O-deethylase (EROD) and aryl hydrocarbon hydroxylase (AHH) activities. There were marked differences in the maximally-induced EROD (1529 pmol mg -1 min -1 ) and AHH (377 pmol mg -1 min - ...
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