The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Introduction: Although CD4-targeted therapy abrogates acute rejection, and may induce permanent graft acceptance in rodents, little is known about the mechanisms of long-term graft survival in these models. Recently, we have shown that treatment with a nondepleting anti-CD4 mAb (RIB-52) induces long-term survival of renal, heart and skin allografts in strong MHC I/II incompatible rat strains.Results:...
Introduction: After allogeneic transplantation the therapy with anti-CD4 monoclonal antibodies (mabs) prevents acute rejection by inhibition of T-cell activation. Experimental data from rodent models demonstrate that anti-CD4mabs binding to distinct epitopes differ in their in vivo immunosuppressive capacity. The aim of our study is to check if this phenomenon can be attributed to differences in...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.