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Cellular morphology is widely applied in digital pathology and is essential for improving our understanding of the basic physiological processes of organisms. One of the main issues of application is to develop efficient methods for cell deformation measurement. We propose an innovative indirect approach to analyze dynamic cell morphology in image sequences. The proposed approach considers both the...
Diffeomorphic demons algorithm is an efficient and robust method in nonrigid image registration. It uses mean squared error as the similarity measure and set the gradient and gray level difference as the interior and exterior force respectively to make the points move. However it cannot deal with multiple modality images. In this paper, mutual information is used as the similarity measure instead...
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