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Serum asialoglycoproteins concentration are increased in patients with hepatic disease. We developed an antibody–lectin sandwich assay that is sensitive and specific to measure asialo-α 1 -acid glycoprotein (AsAGP) concentration in human serum and evaluated it as a biochemical marker for hepatic disease.Serum AsAGP concentration was measured by antibody–lectin sandwich assay with 610 serum...
Serum asialoglycoproteins (desialylated glycoproteins) concentration was reported to be elevated in patients with hepatic disease as compared with that of normal subjects. In this study, we measured serum asialo-α 1 acid glycoprotein (AsAGP) level by a solid-phase sandwich assay in which monoclonal antibody (mAb) to α 1 -acid glycoprotein and galactose-binding lectin, ricinus communis...
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