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Les buts de notre étude ont été d’analyser comment les polymorphismes du gène de la peptidyl-arginine désiminase de type IV (PADI4) participent à la susceptibilité à la polyarthrite rhumatoïde (PR) dans une population égyptienne ; s’ils sont associés à l’activité et à la sévérité de la maladie ; s’ils influencent le taux des anticorps anti-vimentine mutée citrullinée (anti-MCV).Trois polymorphismes...
To investigate whether peptidyl arginine deiminase type IV gene (PADI4) polymorphisms contribute to rheumatoid arthritis (RA) susceptibility in Egyptians, whether they influence disease severity and activity, and whether they affect anti-mutated citrullinated vimentin antibodies (anti-MCV) level.Three PADI4 single nucleotide polymorphisms (SNPs) (PADI4-92, PADI4-96, and PADI4-102) were screened in...
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