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Objectives
It has been widely reported that maternal diabetes impairs oocyte quality. However, the responsible mechanisms remain to be explored. In the present study, we focused on whether SIRT3‐GSK3β pathway mediates the meiotic defects in oocytes from diabetic mice.
Materials and methods
GSK3β functions in mouse oocyte meiosis were first detected by targeted siRNA knockdown. Spindle assembly...
Successful use of oocytes from small follicles (SFs) is of great importance for animal embryo production and human in vitro fertilization with reduced hormone‐related side effects. How in vitro meiotic arrest maintenance (MAM) increases the competence of oocytes is not clear. In this study, pig oocytes recovered from SF of 1–2 mm and medium‐follicles (MF) of 3–6 mm in diameter from abattoir ovaries...
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