The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
The direct functionalization of inert C(sp3)−H bonds under environmentally benign catalytic conditions remains a challenging task in synthetic chemistry. Here, we report an organocatalytic remote C(sp3)−H acylation of amides and cascade cyclization through a radical‐mediated 1,5‐hydrogen atom transfer mechanism using N‐heterocyclic carbene as the catalyst. Notably, a diversity of nitrogen‐containing...
Eine organokatalytische C(sp3)‐H‐Acylierung von Amiden wurde auf der Grundlage einer 1,5‐Wasserstoffatom‐Transferstrategie entwickelt. Im Forschungsartikel von Jun‐Long Li et al. (e202116629) wurden über 120 funktionalisierte δ‐Aminoketone und Isochinolinone in bis zu 99 % Ausbeute unter milden Bedingungen synthetisiert. Mechanistische Untersuchungen, einschließlich Kontrollreaktionen, KIE‐Experimente...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.