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The use of data mining has led to many significant medical discoveries. However, many challenges still exist in using these methods for knowledge discovery within this field given that the large amounts of data medical practitioners collect often creates a curse of dimensionality. To address this challenge, attribute selection approaches have been developed. However, current approaches typically put...
The effect of a radio‐frequency driven, microscale non thermal atmospheric pressure plasma jet operated in helium with vol. 0.3% molecular oxygen gas admixture, on PC‐3 prostate cancer cells has been investigated. The viability of cells exposed to the plasma was found to decrease with increasing plasma exposure time, with apoptosis through caspase and PARP cleavage being observed. High concentrations...
Phospholipase A 2 (PLA 2 ) enzymes (EC3.1.4.4) regulate the release of biologically active fatty acids and lysophospholipids from membrane phospholipid pools. These lipids are also substrates for intracellular biochemical pathways that generate potent autocrine and paracrine lipid mediators such as the eicosanoids and platelet activating factor. These factors, in turn, regulate cell...
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