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SARS‐CoV‐2 Testing
In article number 2107832, Leonidas Bleris, Zhenpeng Qin, and co‐workers develop a plasmonic sensing method for loop‐mediated isothermal amplification (plasmonic LAMP). It turns complex amplicons into short single‐strand DNA for sequence‐specific detection with plasmonic nanoprobes, achieving improved detection sensitivity and specificity.
The ability to detect pathogens specifically and sensitively is critical to combat infectious diseases outbreaks and pandemics. Colorimetric assays involving loop‐mediated isothermal amplification (LAMP) provide simple readouts yet suffer from the intrinsic non‐template amplification. Herein, a highly specific and sensitive assay relying on plasmonic sensing of LAMP amplicons via DNA hybridization,...
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