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Microbubbles (MBs) coated by surfactant or polymer have been shown to be the most effective contrast agents for diagnostic ultrasound contrast imaging and targeted molecular imaging. With the development of both diagnostic and therapeutic applications of ultrasound contrast agents (UCAs), there is a demand for new preparation technologies to provide a high degree of control over MB size, composition,...
Using ultrasonic contrast microbubbles as acoustic biomarkers and drug carrier vehicles by conjugating tumor specific antibody to microbubbles has shown great potential in ultrasonic tumor molecular imaging or drug-delivery and therapy. Microbubble probe targeting efficiency is one of the major challenges. In this study, we developed a novel method to evaluate the targeting capability and efficiency...
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