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The importance of Noble prize winning “Patch Clamp Technique” is well documented. However, Patch Clamp Technique is very expensive and hence hinders research in developing countries. In this paper detection, processing and recording of ultra low current from induced cells by using transimpedence amplifier is described. The sensitivity of the proposed amplifier is in the range of femto amperes (fA)...
This paper aims to expand the work in by modeling breast tumors, containing a large number of cells, of different spatial distributions and division stages. Malignant breast tumors were found to exhibit an irregular shape whereas benign tumors were found to have a smooth circular shape. Therefore, the goal of this work is to study the effect of the different cell configurations on the electric signals.
Labor prediction using the electrohysterogram has immediate clinical applications and has been the aim of several studies in recent years. Studies using various linear methods such as classic spectral analysis do not give clinically useful results. In this paper we present the use of two methods that investigate nonlinearity to predict normal labor. We show the comparison between a linear method that...
The analysis of the electrical activity of the uterus recorded externally, the electrohysterogram (EHG), may find an application in the prediction of labor. In the literature parameters that are supposed to be related to the excitability of the uterine cells have almost exclusively been used for this purpose. In the present paper we evaluate the possible use of synchronization parameters for EHG measured...
This study presents a model to simulate the electrophysiological activities of multiple Michigan Cancer Foundation-7 (MCF-7) cells, the most studied breast cancer cell line. The intercellular spacing of MCF-7 cells is estimated using the effective diffusion coefficient. Nonuniform finite-difference discretization is implemented to accommodate for the contrast in size between the intercellular spacing...
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