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Purpose: Taylor (Lancet 343, 1994, 86) reported about hot spot mutations at codon 249 of the p53 gene in lung cancers of former uranium miners in the USA. We started an investigation in order to get more knowledge about similar mutations in former German uranium miners.Methods: Until now we investigated 21 former German uranium miners with lung cancers (17 squamous cell cancers). Tumor tissue was...
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