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Background Moderate-to-severe obstructive sleep apnea (OSA) has been documented in about 20% of patients with heart failure and reduced ejection fraction (HF-REF). Continuous positive airway pressure (CPAP) is the gold standard for OSA treatment, but very few studies have investigated the effects of CPAP on quality of life, cardiac function, and outcome in HF-REF patients. The Automatic Positive A...
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