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L. De Cola and co‐workers report a nanocomposite hydrogel able to induce in vitro chemotaxis of stem cells on page 4881. The cover image shows a nanocomposite hydrogel containing mesoporous silica nanoparticles integrated into the polymeric network. The controlled release of SDF‐1α from the hydrogel induced the chemotaxis of stem cells, while the optimal mechanical properties enhanced stem cells proliferation...
The challenge of mimicking the extracellular matrix with artificial scaffolds that are able to reduce immunoresponse is still unmet. Recent findings have shown that mesenchymal stem cells (MSC) infiltrating into the implanted scaffold have effects on the implant integration by improving the healing process. Toward this aim, a novel polyamidoamine‐based nanocomposite hydrogel is synthesized, cross‐linked...
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