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Curcumin is the active compound in the extract of Curcuma longa rhizomes with anti-inflammatory properties mediated by inhibition of intracellular signalling. SOCS and MAPKinases are involved in the signalling events controlling the expression of IL-6, TNF-α and PGE 2 , which have important roles on chronic inflammatory diseases. The aim was to assess if these pathways are involved in curcumin-mediated...
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