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Isatin is an endogenous indole, which has a distinct and discontinuous distribution in the brain and exhibits a wide range of physiological and pharmacological effects.In the present study, we have demonstrated that atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP) inhibited [ 3 H]isatin binding to rat brain sections and isolated membrane fractions. Isatin itself antagonised...
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