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Non‐obstructive azoospermia (NOA) represents one of the most serious forms of male infertility caused by spermatogenic failure. Despite multiple genes found to be associated with human NOA, the genetic basis of this idiopathic disease remains largely unknown. FBXO43 is a direct inhibitor of the anaphase‐promoting complex/cyclosome (APC/C) E3 ligase and crucially important in mouse spermatogenesis...